Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17678623 | 0.86 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL30705602 | 0.81 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL24159176 | 0.80 | MAP2K1 (0.37) | KDM4EALDH1A1HSD17B10HPGDPARP1 | |
| SCHEMBL30810912 | 0.79 | KDM4E (0.72) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL31376414 | 0.79 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL31376415 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10HPGDPARP1 | |
| SCHEMBL20939569 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL32662518 | 0.75 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL20939530 | 0.74 | TNKS2 (0.38) | KDM4EALDH1A1HSD17B10HPGDHTT | |
| SCHEMBL30705455 | 0.74 | KDM4E (0.31) | KDM4EALDH1A1HSD17B10HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403787-A | 3- (Sulfonyl or iminosulfonyl) prop-2-en-1-yl ] -2-oxo-1, 2-dihydropyridine-3-carboxamide derivatives | 福临德治疗公司 | 2025-02-07 | — | — | CN | claimed |
| CN-119403787-A | 3- (Sulfonyl or iminosulfonyl) prop-2-en-1-yl ] -2-oxo-1, 2-dihydropyridine-3-carboxamide derivatives | 福临德治疗公司 | 2025-02-07 | — | — | CN | disclosed |