Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.35 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632735 | 0.75 | SMN1; SMN2 (0.53) | GAASMN1; SMN2CYP17A1TSHRLMNA | |
| SCHEMBL5726614 | 0.70 | TDO2 (0.49) | GAASMN1; SMN2CYP17A1TSHRTDO2 | |
| SCHEMBL15647598 | 0.69 | SMN1; SMN2 (0.62) | GAASMN1; SMN2CYP17A1TSHRLMNA | |
| SCHEMBL1242879 | 0.69 | SMN1; SMN2 (0.87) | GAASMN1; SMN2CYP17A1TSHRLMNA | |
| SCHEMBL6420068 | 0.69 | SMN1; SMN2 (0.72) | GAASMN1; SMN2CYP17A1TSHRLMNA | |
| SCHEMBL24196560 | 0.68 | IDO1 (0.49) | GAASMN1; SMN2CYP17A1TSHRLMNA | |
| SCHEMBL30270464 | 0.68 | IDO1 (0.49) | GAASMN1; SMN2CYP17A1TSHRLMNA | |
| SCHEMBL27721185 | 0.68 | SLC6A2 (0.38) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20001897 | 0.68 | CYP3A4 (0.47) | GAASMN1; SMN2CYP17A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL9030540 | 0.67 | SMN1; SMN2 (0.70) | GAASMN1; SMN2CYP17A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954525-B | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2023-12-26 | — | — | CN | disclosed |