SCHEMBL30706138

SCHEMBL30706138

CNC(=O)COc1cc2cc(Nc3nc(N4CCC(C(=O)OC(C)(C)C)CC4)ncc3Cl)ccc2n(C)c1=O

nearest known ligand 0.71

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BCL6 P41182 20/20 0.71
▸ MELK Q14680 1/20 0.71
▸ NCOR2 Q9Y618 6/20 0.70
▸ CHRM4 P08173 1/20 0.61
▸ BCL6B Q8N143 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20284725 0.91 BCL6 (0.79) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284233 0.91 BCL6 (0.76) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL23267189 0.90 BCL6 (0.75) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL31554644 0.89 BCL6 (0.68) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284198 0.89 BCL6 (0.78) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL22932328 0.89 BCL6 (0.78) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284724 0.89 BCL6 (0.83) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL21774733 0.89 BCL6 (0.77) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL23267254 0.88 BCL6 (0.77) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284538 0.88 BCL6 (0.72) BCL6MELKNCOR2CHRM4BCL6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4536649-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-04-16 — — EP disclosed
WO-2023244918-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2023-12-21 — — WO disclosed
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