SCHEMBL30706175

SCHEMBL30706175

Cn1nc(C2CCC(=O)NC2=O)c2ccc(NCC3CCC(CNC(=O)OC(C)(C)C)CC3)cc21

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 12/20 0.63
▸ CRBN Q96SW2 12/20 0.63
▸ ACACB O00763 5/20 0.38
▸ ACACA Q13085 3/20 0.38
▸ DRD2 P14416 1/20 0.38
▸ ADORA3 P0DMS8 1/20 0.37
▸ ADORA2A P29274 1/20 0.37
▸ ADORA2B P29275 1/20 0.37
▸ ADORA1 P30542 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30705885 0.92 DDB1 (0.73) DDB1CRBNACACBACACADRD2
SCHEMBL30661576 0.86 DDB1 (0.72) DDB1CRBN
SCHEMBL30793998 0.85 DDB1 (0.74) DDB1CRBN
SCHEMBL30794089 0.85 DDB1 (0.74) DDB1CRBN
SCHEMBL31333213 0.85 DDB1 (0.55) DDB1CRBNACACBACACADRD2
SCHEMBL30706047 0.84 DDB1 (0.57) DDB1CRBNACACBACACA
SCHEMBL30706148 0.84 DDB1 (0.70) DDB1CRBN
SCHEMBL30705914 0.84 DDB1 (0.70) DDB1CRBN
SCHEMBL30706015 0.84 CRBN (0.63) DDB1CRBN
SCHEMBL31333942 0.83 DDB1 (0.55) DDB1CRBNACACBACACADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4536649-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-04-16 — — EP disclosed
WO-2023244918-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2023-12-21 — — WO disclosed
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