Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 11/20 | 0.74 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.74 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30793998 | 1.00 | DDB1 (0.74) | DDB1CRBNIDO1TDO2JAK2 | |
| SCHEMBL30706148 | 0.95 | DDB1 (0.70) | DDB1CRBNIDO1TDO2JAK2 | |
| SCHEMBL30705914 | 0.95 | DDB1 (0.70) | DDB1CRBNIDO1TDO2JAK2 | |
| SCHEMBL30706020 | 0.88 | DDB1 (0.68) | DDB1CRBNGPR119 | |
| SCHEMBL30029207 | 0.88 | DDB1 (0.81) | DDB1CRBNGPR119 | |
| SCHEMBL30661527 | 0.85 | DDB1 (0.80) | DDB1CRBNJAK2JAK3 | |
| SCHEMBL30706175 | 0.85 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL20805490 | 0.85 | DDB1 (1.00) | DDB1CRBNGPR119 | |
| SCHEMBL29984027 | 0.85 | DDB1 (1.00) | DDB1CRBNGPR119 | |
| SCHEMBL30706016 | 0.85 | DDB1 (0.67) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536658-A1 | 1,8-NAPHTHYRIDIN-2-ONE HETEROBIFUNCTIONAL BCL6 DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |