Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827007 | 0.86 | POLB (0.37) | KDM4CKMT2APOLBTDP1ALDH1A1 | |
| SCHEMBL17076660 | 0.85 | OPRM1 (0.42) | IRAK4KMT2APOLBTDP1OPRM1 | |
| SCHEMBL31460230 | 0.81 | IRAK4 (0.35) | IRAK4KDM4CKMT2APOLBTDP1 | |
| SCHEMBL27663461 | 0.77 | PIM1 (0.48) | IRAK4 | |
| SCHEMBL27663462 | 0.77 | PIM1 (0.48) | IRAK4 | |
| SCHEMBL28761039 | 0.77 | PIM1 (0.48) | IRAK4 | |
| SCHEMBL27682836 | 0.75 | PARP1 (0.47) | IRAK4KMT2AMAPTCYP2D6 | |
| SCHEMBL1080225 | 0.74 | TMEM97 (0.45) | KDM4CKMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2662008 | 0.74 | TMEM97 (0.45) | KDM4CKMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30707190 | 0.73 | ACKR3 (0.34) | IRAK4POLBSMN1; SMN2OPRM1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540255-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2025080986-A1 | AMIDE COMPOUNDS | QUANTX BIOSCIENCES US, INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| WO-2023244615-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-12-21 | — | — | WO | disclosed |