Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644389 | 1.00 | KMT2A (0.46) | KMT2ALMNANPC1RAB9AMAPT | |
| SCHEMBL30522176 | 0.87 | KMT2A (0.55) | KMT2ALMNANPC1RAB9AALDH1A1 | |
| SCHEMBL643938 | 0.87 | CA12 (0.47) | KMT2ALMNANPC1RAB9ACNR2 | |
| SCHEMBL25139946 | 0.87 | KMT2A (0.55) | KMT2ALMNANPC1RAB9AALDH1A1 | |
| SCHEMBL25139948 | 0.83 | KMT2A (0.47) | KMT2ALMNANPC1RAB9AMAPT | |
| SCHEMBL25139713 | 0.83 | KMT2A (0.47) | KMT2ALMNANPC1RAB9AMAPT | |
| SCHEMBL3626546 | 0.83 | LMNA (0.39) | KMT2ALMNANPC1RAB9AMAPT | |
| SCHEMBL2321653 | 0.82 | KMT2A (0.41) | KMT2ALMNANPC1RAB9AMAPT | |
| SCHEMBL30522177 | 0.79 | KMT2A (0.42) | KMT2ALMNANPC1RAB9AMAPT | |
| SCHEMBL30522178 | 0.79 | KMT2A (0.42) | KMT2ALMNANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |