Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | CTH | P32929 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22230365 | 1.00 | NR4A1 (0.47) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL14334435 | 1.00 | NR4A1 (0.47) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL22230368 | 1.00 | NR4A1 (0.47) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL29504028 | 1.00 | NR4A1 (0.47) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL16746574 | 1.00 | NR4A1 (0.47) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL12315085 | 1.00 | NR4A1 (0.47) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL29662301 | 1.00 | NR4A1 (0.47) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL15157684 | 0.79 | GPR3 (0.35) | GPR3 | |
| SCHEMBL29060308 | 0.79 | GPR3 (0.35) | GPR3 | |
| SCHEMBL15166344 | 0.79 | GPR3 (0.35) | GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |