Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069066 | 1.00 | NPC1 (0.38) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15068776 | 1.00 | NPC1 (0.38) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15068551 | 1.00 | NPC1 (0.38) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15069027 | 0.91 | NPC1 (0.37) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15068856 | 0.91 | NPC1 (0.37) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL27262304 | 0.91 | NPC1 (0.37) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21301319 | 0.91 | NPC1 (0.37) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21324749 | 0.91 | NPC1 (0.37) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21301234 | 0.91 | NPC1 (0.37) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15068502 | 0.91 | NPC1 (0.38) | NPC1RAB9AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006287-A2 | ANTIVIRAL COMPOUNDS USEFUL AGAINST SARS-COV-2 | UNIVERSITY OF KANSAS (US) | 2024-01-04 | — | — | WO | claimed |
| WO-2024006287-A2 | ANTIVIRAL COMPOUNDS USEFUL AGAINST SARS-COV-2 | UNIVERSITY OF KANSAS (US) | 2024-01-04 | — | — | WO | disclosed |