Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22904598 | 0.88 | MEN1 (0.45) | KMT2AGAASMN1; SMN2MEN1CASP1 | |
| SCHEMBL6049525 | 0.86 | MEN1 (0.50) | KMT2AGAASMN1; SMN2MEN1CASP1 | |
| SCHEMBL29937045 | 0.86 | NOTUM (0.40) | KMT2AGAASMN1; SMN2MEN1CASP1 | |
| SCHEMBL26694790 | 0.86 | NOTUM (0.40) | KMT2AGAASMN1; SMN2MEN1CASP1 | |
| SCHEMBL7465410 | 0.86 | MEN1 (0.56) | KMT2AGAASMN1; SMN2MEN1CASP1 | |
| SCHEMBL8844912 | 0.85 | KMT2A (0.49) | KMT2AGAASMN1; SMN2MEN1CASP1 | |
| SCHEMBL1366941 | 0.84 | KMT2A (0.48) | KMT2AGAASMN1; SMN2MEN1TDP1 | |
| SCHEMBL22904512 | 0.84 | SMN1; SMN2 (0.48) | KMT2AGAASMN1; SMN2MEN1TDP1 | |
| SCHEMBL22904151 | 0.80 | MEN1 (0.47) | KMT2AGAASMN1; SMN2MEN1TDP1 | |
| SCHEMBL22904479 | 0.79 | KMT2A (0.52) | KMT2AGAASMN1; SMN2MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547666-A1 | METHODS FOR TREATMENT OF CANCER | Frontier Medicines Corporation (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006445-A1 | METHODS FOR TREATMENT OF CANCER | FRONTIER MEDICINES CORPORATION (US) | 2024-01-04 | — | — | WO | disclosed |