Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL7193304 | 0.89 | SLC34A1 (0.80) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL7191766 | 0.89 | SLC34A1 (0.80) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL10683945 | 0.89 | SLC34A1 (0.80) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL8384640 | 0.89 | SLC34A1 (0.80) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL516073 | 0.89 | SLC34A1 (0.80) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL25210375 | 0.89 | — | — | |
| Phosphoric Acid SCHEMBL186335 | 0.89 | SLC34A1 (0.80) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL21990207 | 0.89 | — | — | |
| Phosphoric Acid SCHEMBL21815665 | 0.89 | SLC34A1 (0.80) | SLC34A1LMNACA2KDM4ECYP2C19 | |
| Phosphoric Acid SCHEMBL6388831 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758899-B2 | Enhanced bonding layers on titanium materials | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2014-06-24 | — | — | US | disclosed |
| US-20120012033-A1 | ENHANCED BONDING LAYERS ON TITANIUM MATERIALS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-01-19 | — | — | US | disclosed |
| US-8092585-B2 | Enhanced bonding layers on titanium materials | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110093082-A1 | ENHANCED BONDING LAYERS ON TITANIUM MATERIALS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2011-04-21 | — | — | US | disclosed |
| US-7815963-B2 | Enhanced bonding layers on titanium materials | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2010-10-19 | — | — | US | disclosed |
| US-7569285-B2 | Enhanced bonding layers on titanium materials | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-08-04 | — | — | US | disclosed |
| US-20080206443-A1 | ENHANCED BONDING LAYERS ON TITANIUM MATERIALS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2008-08-28 | — | — | US | disclosed |
| US-20040001959-A1 | Enhanced bonding layers on titanium materials | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-01-01 | — | — | US | disclosed |