Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26603475 | 1.00 | GAA (0.66) | GAAHPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL26603300 | 0.91 | GAA (0.80) | GAAHPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL30626150 | 0.91 | GAA (0.80) | GAAHPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL26603271 | 0.89 | HIF1A (0.53) | GAAALDH1A1L3MBTL1PKMRECQL | |
| SCHEMBL30709175 | 0.89 | HIF1A (0.53) | GAAALDH1A1L3MBTL1PKMRECQL | |
| SCHEMBL26603519 | 0.84 | GAA (0.75) | GAAHPGDHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL30709079 | 0.84 | GAA (0.75) | GAAHPGDHSD17B10ALDH1A1NR1H4 | |
| SCHEMBL26603458 | 0.83 | GAA (0.71) | GAAHPGDHSD17B10ALDH1A1AKR1C3 | |
| SCHEMBL26603495 | 0.83 | GAA (0.70) | GAAHPGDHSD17B10ALDH1A1AKR1C3 | |
| SCHEMBL26603318 | 0.83 | ALDH1A1 (0.69) | GAAHPGDHSD17B10ALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903563-A | GPCR modulators and uses thereof | 北京昌平实验室 | 2023-10-20 | — | — | CN | disclosed |