Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30711161 | 0.82 | SLC16A3 (0.48) | SLC16A3KDM4ETSHRHSD17B10FABP3 | |
| SCHEMBL19410197 | 0.81 | SLC16A3 (0.46) | SLC16A3KDM4EAKR1B1MAPTRECQL | |
| SCHEMBL19410131 | 0.78 | SLC16A3 (0.43) | SLC16A3KDM4EAKR1B1MAPTRECQL | |
| SCHEMBL23908941 | 0.76 | KDM4E (0.46) | SLC16A3KDM4ETSHRHSD17B10AKR1B1 | |
| SCHEMBL22061004 | 0.74 | MAPT (0.55) | SLC16A3HSD17B10AKR1B1MAPTS1PR2 | |
| SCHEMBL23909094 | 0.73 | MAPT (0.64) | TSHRAKR1B1MAPTRECQLALDH1A1 | |
| SCHEMBL23909083 | 0.73 | KDM4E (0.51) | SLC16A3KDM4ETSHRHSD17B10MAPT | |
| SCHEMBL19410138 | 0.72 | SLC16A3 (0.46) | SLC16A3KDM4ETSHRHSD17B10MAPT | |
| SCHEMBL19410139 | 0.72 | SLC16A3 (0.46) | SLC16A3KDM4ETSHRHSD17B10MAPT | |
| SCHEMBL30711162 | 0.72 | SLC16A3 (0.46) | SLC16A3KDM4ETSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997698-B | Immunomodulatory agents acting as PD-1 antagonists | 百时美施贵宝公司 | 2023-12-26 | — | — | CN | disclosed |