Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410138 | 1.00 | SLC16A3 (0.46) | SLC16A3ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL19410139 | 1.00 | SLC16A3 (0.46) | SLC16A3ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL19410197 | 0.84 | SLC16A3 (0.46) | SLC16A3ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL30711161 | 0.81 | SLC16A3 (0.48) | SLC16A3ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL19410121 | 0.78 | SLC16A3 (0.48) | SLC16A3ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL30711155 | 0.78 | SLC16A3 (0.48) | SLC16A3ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL19410123 | 0.78 | SLC16A3 (0.48) | SLC16A3ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL16099677 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL7434865 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL30002479 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997698-B | Immunomodulatory agents acting as PD-1 antagonists | 百时美施贵宝公司 | 2023-12-26 | — | — | CN | disclosed |