Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ADH5 | P11766 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30711337 | 0.87 | TSHR (0.41) | HCAR2MAOAHDAC3HDAC4HDAC7 | |
| SCHEMBL30711182 | 0.87 | TSHR (0.42) | PROKR1P2RY14EGLN1KDM1AHSD17B10 | |
| SCHEMBL30711351 | 0.87 | PROKR1 (0.40) | PROKR1P2RY14KDM1A | |
| SCHEMBL30711334 | 0.86 | HCRTR1 (0.36) | HSD11B1P2RY14HSD17B10 | |
| SCHEMBL30711318 | 0.85 | L3MBTL1 (0.34) | HCAR2CHEK1P2RY14EGLN1KDM1A | |
| SCHEMBL30711285 | 0.81 | HCAR2 (0.39) | HCAR2P2RY14 | |
| SCHEMBL30711308 | 0.81 | HCAR2 (0.44) | HCAR2HDAC4P2RY14 | |
| SCHEMBL30711241 | 0.80 | JMJD6 (0.37) | CHEK1HSD11B1ADH5P2RY14 | |
| SCHEMBL30711259 | 0.79 | AKR1C3 (0.44) | P2RY14 | |
| SCHEMBL30711292 | 0.79 | P2RY14 (0.42) | P2RY14HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023246677-A1 | INDOLE-PHENYLPIPERIDINE COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 深圳信立泰药业股份有限公司 | 2023-12-28 | — | — | WO | disclosed |