Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30055934 | 0.78 | — | — | |
| SCHEMBL30711664 | 0.76 | — | — | |
| SCHEMBL30776869 | 0.73 | KMT2A (0.52) | CRHBPCRHR2 | |
| SCHEMBL28900768 | 0.72 | TSHR (0.40) | — | |
| SCHEMBL11179340 | 0.72 | ALDH1A1 (0.31) | CRHBPCRHR2 | |
| SCHEMBL29807411 | 0.71 | — | — | |
| SCHEMBL10948087 | 0.70 | ALDH1A1 (0.30) | CRHBPCRHR2 | |
| SCHEMBL30173704 | 0.70 | MEN1 (0.33) | — | |
| SCHEMBL21288180 | 0.69 | — | — | |
| SCHEMBL28390801 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |