Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21062063 | 1.00 | PDE4D (0.38) | PDE4DPDE10ANPC1CYP1A2MAPT | |
| SCHEMBL30712009 | 0.88 | PDE4D (0.40) | PDE4D | |
| SCHEMBL23088650 | 0.88 | PDE4D (0.40) | PDE4D | |
| SCHEMBL23088619 | 0.77 | PDE4D (0.62) | PDE4DPDE10A | |
| SCHEMBL30712004 | 0.77 | PDE4D (0.62) | PDE4DPDE10A | |
| SCHEMBL23088621 | 0.77 | PDE4D (0.62) | PDE4DPDE10A | |
| SCHEMBL23088633 | 0.74 | DRD2 (0.32) | — | |
| SCHEMBL30712010 | 0.74 | DRD2 (0.32) | — | |
| SCHEMBL23098518 | 0.74 | PDE4D (0.43) | PDE4D | |
| SCHEMBL21062072 | 0.73 | PDE4D (0.39) | PDE4DPDE10ANPC1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111727191-B | Substituted azetidine dihydro-thienopyridines and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-01-05 | — | — | CN | disclosed |