Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29223283 | 0.83 | RHEB (0.53) | KDM4EHSD17B10HTTGAATP53 | |
| SCHEMBL28025570 | 0.79 | SLC22A6 (0.50) | KDM4EHSD17B10HTTGAAALDH1A1 | |
| SCHEMBL30483746 | 0.78 | RHEB (0.41) | KDM4EALDH1A1MTNR1AMTNR1BACHE | |
| SCHEMBL6270065 | 0.78 | RHEB (0.41) | KDM4EALDH1A1MTNR1AMTNR1BACHE | |
| SCHEMBL16265058 | 0.77 | KDM4E (0.59) | KDM4EHSD17B10HTTGAATP53 | |
| SCHEMBL594038 | 0.72 | SLC22A6 (0.63) | KDM4EHSD17B10TP53ALDH1A1HPGD | |
| SCHEMBL29511854 | 0.72 | SLC22A6 (0.63) | KDM4EHSD17B10TP53ALDH1A1HPGD | |
| SCHEMBL29783527 | 0.71 | NOTUM (0.41) | KDM4EHSD17B10ALDH1A1HPGDMTNR1A | |
| SCHEMBL27222251 | 0.71 | NOTUM (0.41) | KDM4EHSD17B10ALDH1A1HPGDMTNR1A | |
| SCHEMBL16450253 | 0.71 | KDM4E (0.53) | KDM4EHSD17B10HTTGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635492-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4551212-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024035757-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |