Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.74 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | HTR2C | P28335 | 7/20 | 0.60 |
| ▸ | HTR2B | P41595 | 6/20 | 0.59 |
| ▸ | HTR1D | P28221 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 1/20 | 0.59 |
| ▸ | HTR1E | P28566 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HTR5A | P47898 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30183441 | 1.00 | HTR2A (0.74) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL25008718 | 0.92 | HTR2A (0.70) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL29992340 | 0.90 | HTR2A (0.76) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL25030287 | 0.90 | HTR2A (0.76) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL25008884 | 0.89 | HTR2A (0.67) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL25008706 | 0.89 | HTR2A (0.67) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL25008704 | 0.89 | HTR2A (0.67) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL25008717 | 0.89 | HTR2A (0.67) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL25008687 | 0.89 | HTR2A (0.67) | HTR2AHTR1AHTR2CHTR2BHTR1D | |
| SCHEMBL31708127 | 0.86 | HTR2A (0.69) | HTR2AHTR1AHTR2CHTR2BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122474-A1 | 4-HYDROXY-N-PROPYLTRYPTAMINE | CAAMTECH, INC. (US) | 2025-06-12 | — | — | WO | claimed |
| EP-4635492-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| WO-2025122474-A1 | 4-HYDROXY-N-PROPYLTRYPTAMINE | CAAMTECH, INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| WO-2025122474-A1 | 4-HYDROXY-N-PROPYLTRYPTAMINE | CAAMTECH, INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| EP-4551212-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024035757-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |