SCHEMBL25030287

SCHEMBL25030287

CCNCCc1c[nH]c2cccc(O)c12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 12/20 0.76
▸ HTR1A P08908 3/20 0.62
▸ HTR2C P28335 7/20 0.61
▸ HTR2B P41595 6/20 0.61
▸ DRD1 P21728 1/20 0.61
▸ HTR1D P28221 1/20 0.61
▸ HTR1B P28222 1/20 0.61
▸ HTR1E P28566 1/20 0.61
▸ ADORA2A P29274 1/20 0.61
▸ ADORA2B P29275 1/20 0.61
▸ HTR7 P34969 1/20 0.61
▸ DRD3 P35462 1/20 0.61
▸ HTR5A P47898 1/20 0.61
▸ HTR6 P50406 1/20 0.61
▸ GAA P10253 2/20 0.52
▸ KDM4E B2RXH2 2/20 0.52
▸ ALDH1A1 P00352 2/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ MAPT P10636 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29992340 1.00 HTR2A (0.76) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL30712085 0.90 HTR2A (0.74) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL30183441 0.90 HTR2A (0.74) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL25008718 0.87 HTR2A (0.70) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL31614648 0.87 HTR2A (0.74) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL29557008 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL26965688 0.86 HTR2A (0.63) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL12352648 0.86 HTR2A (1.00) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL27134372 0.86 HTR2A (0.71) HTR2AHTR1AHTR2CHTR2BDRD1
SCHEMBL25008717 0.85 HTR2A (0.67) HTR2AHTR1AHTR2CHTR2BDRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4635492-A2 TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS Gilgamesh Pharmaceuticals, Inc. (US) 2025-10-22 — — EP disclosed
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 — — US disclosed
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS SYNAPTIVE THERAPEUTICS, LLC 2024-11-07 — — US disclosed
CN-118055766-A Magic and non-magic serotonin receptor agonist and its preparing process and usage 库莱恩有限责任公司 2024-05-17 — — CN disclosed
US-20230405026-A1 A Method of Treating Depression by Immune Modulation MYND LIFE SCIENCES INC (CA) 2023-12-21 — — US disclosed
US-11780807-B2 Benzoselenophene, benzothiophene, and benzofuran analogs and methods of modulating the serotonin 5-HT2C receptor Kuleon, LLC (US) 2023-10-10 — — US disclosed
US-11780807-B2 Benzoselenophene, benzothiophene, and benzofuran analogs and methods of modulating the serotonin 5-HT2C receptor Kuleon, LLC (US) 2023-10-10 — — US disclosed
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR Kuleon, LLC (US) 2023-08-17 — — US disclosed
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR Kuleon, LLC (US) 2023-08-17 — — US disclosed
WO-2023018864-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240366638-A1 PSILOCYBIN ANALOGS FOR TREATING PSYCHOLOGICAL DISORDERS HTR1B, HTR2B, PNMT HTR2A 5/4885HTR1A 8/4885HTR2C 4/4885
US-11780807-B2 Benzoselenophene, benzothiophene, and benzofuran analogs and methods of modulating the serotonin 5-HT2C receptor HTR2C, HTR2A, HTR3C HTR2A 2/4885HTR1A 8/4885HTR2C 1/4885
US-20230405026-A1 A Method of Treating Depression by Immune Modulation ABCF1, ABCF2, ABCB4 HTR2A 377/4885HTR1A 507/4885HTR2C 1196/4885
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR HTR2C, HTR2A, HTR3B HTR2A 2/4885HTR1A 9/4885HTR2C 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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