SCHEMBL30712834

SCHEMBL30712834

Cc1cc2cccc(C)c2[nH]1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.56
DDO Q99489 1/20 0.56
ALDH1A1 P00352 5/20 0.55
GAA P10253 2/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
NSD2 O96028 1/20 0.46
KDM4E B2RXH2 7/20 0.44
HRH4 Q9H3N8 3/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 2/20 0.42
AHR P35869 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP1A2 P05177 1/20 0.41
GLA P06280 1/20 0.41
KIF11 P52732 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1093711 1.00 DAO (0.56) DAODDOALDH1A1GAAPOLB
SCHEMBL15045560 0.84 ALDH1A1 (0.44) DAODDOALDH1A1GAAPOLB
SCHEMBL19705440 0.80 KDM4E (0.42) DAODDOALDH1A1GAAPOLB
SCHEMBL12778103 0.80 DAO (0.55) DAODDOALDH1A1GAAPOLB
SCHEMBL12755271 0.79 DAO (0.50) DAODDOALDH1A1GAAPOLB
SCHEMBL30963688 0.78 DAO (0.53) DAODDOALDH1A1GAAPOLB
SCHEMBL3293424 0.78 DAO (0.53) DAODDOALDH1A1GAAPOLB
SCHEMBL30939499 0.78 DAO (0.53) DAODDOALDH1A1NSD2KDM4E
SCHEMBL28597310 0.78 DAO (0.62) DAODDOALDH1A1MAPTNSD2
SCHEMBL597517 0.78 CA12 (0.50) DAODDOALDH1A1GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924960-A Method for synthesizing 3-indolyl benzoquinone compound 郑州大学 2023-10-24 CN disclosed