Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.61 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.51 |
| ▸ | VIPR1 | P32241 | 1/20 | 0.50 |
| ▸ | VIPR2 | P41587 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612206 | 0.95 | BACE1 (0.54) | BACE1MDM4MDM2F2BACE2 | |
| SCHEMBL30839323 | 0.91 | NPY4R (0.59) | BACE1F2 | |
| SCHEMBL30350355 | 0.90 | BACE1 (0.61) | BACE1CTSDVIPR1VIPR2 | |
| SCHEMBL30502848 | 0.89 | BACE1 (0.58) | BACE1VIPR1VIPR2 | |
| SCHEMBL29612075 | 0.89 | NPY4R (0.60) | F2 | |
| SCHEMBL31514343 | 0.89 | F2 (0.56) | BACE1CTSDMDM4MDM2F2 | |
| SCHEMBL30342388 | 0.88 | F2 (0.52) | BACE1CTSDF2VIPR1VIPR2 | |
| SCHEMBL30836857 | 0.88 | BACE1 (0.55) | BACE1CTSD | |
| SCHEMBL31157662 | 0.88 | ENPEP (0.52) | BACE1MDM4MDM2 | |
| SCHEMBL30239836 | 0.88 | BACE1 (0.58) | BACE1CTSDBACE2VIPR1VIPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447584-A | Hirudin with anticoagulant, antithrombotic and anti-inflammatory activities and application thereof | 滨州医学院 | 2024-01-26 | — | — | CN | claimed |
| CN-117447584-A | Hirudin with anticoagulant, antithrombotic and anti-inflammatory activities and application thereof | 滨州医学院 | 2024-01-26 | — | — | CN | disclosed |