⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851903 | 0.78 | — | — | |
| SCHEMBL28858899 | 0.77 | KDM4E (0.31) | — | |
| SCHEMBL11174518 | 0.71 | DPP4 (0.37) | — | |
| Hydrochloric Acid SCHEMBL30713516 | 0.69 | — | — | |
| SCHEMBL8186821 | 0.67 | — | — | |
| SCHEMBL14845674 | 0.66 | — | — | |
| SCHEMBL24817274 | 0.66 | — | — | |
| SCHEMBL31485054 | 0.65 | JAK2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL30713629 | 0.64 | GNAI3 (0.31) | — | |
| SCHEMBL28005830 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368666-A1 | INDAZOLE COMPOUNDS | TYRA BIOSCIENCES INC (US) | 2025-12-04 | — | — | US | disclosed |
| EP-4547656-A1 | INDAZOLE COMPOUNDS | Tyra Biosciences, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| CN-119731165-A | Indazole compounds | 泰拉生物科学公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2024006897-A1 | INDAZOLE COMPOUNDS | TYRA BIOSCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |