SCHEMBL30713609

SCHEMBL30713609

CC(C)(C)[Si](C)(C)Oc1ccc2c(c(I)nn2C2CCCCO2)c1F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.31
CYP4A11 Q02928 2/20 0.31
RET P07949 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24606751 0.87 ATR (0.30) CYP4F2CYP4A11RET
SCHEMBL31190804 0.85 CYP4F2 (0.33) CYP4F2CYP4A11RET
SCHEMBL30540775 0.84 RET (0.32) CYP4F2CYP4A11RET
SCHEMBL20765166 0.82 CYP4F2 (0.35) CYP4F2CYP4A11RET
SCHEMBL29712202 0.80 CYP4F2 (0.34) CYP4F2CYP4A11RET
SCHEMBL24607090 0.80 CYP4F2 (0.34) CYP4F2CYP4A11RET
SCHEMBL19204904 0.80 CYP4F2 (0.39) CYP4F2CYP4A11RET
SCHEMBL30713479 0.78 CYP4F2 (0.40) CYP4F2CYP4A11RET
SCHEMBL16100337 0.77 CYP4F2 (0.36) CYP4F2CYP4A11RET
SCHEMBL298676 0.77 CYP4F2 (0.36) CYP4F2CYP4A11RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547656-A1 INDAZOLE COMPOUNDS Tyra Biosciences, Inc. (US) 2025-05-07 EP disclosed
CN-119731165-A Indazole compounds 泰拉生物科学公司 2025-03-28 CN disclosed
WO-2024006897-A1 INDAZOLE COMPOUNDS TYRA BIOSCIENCES, INC. (US) 2024-01-04 WO disclosed