SCHEMBL31190804

SCHEMBL31190804

CC(C)(C)[Si](C)(C)Oc1cccc2c1c(I)nn2C1CCCCO1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
RET P07949 2/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30540754 0.85 EGFR (0.37) CYP4F2CYP4A11RET
SCHEMBL30713609 0.85 CYP4F2 (0.31) CYP4F2CYP4A11RET
SCHEMBL24606751 0.85 ATR (0.30) CYP4F2CYP4A11RET
SCHEMBL31712815 0.85 CYP4F2 (0.31) CYP4F2CYP4A11RET
SCHEMBL30540775 0.83 RET (0.32) CYP4F2CYP4A11RET
SCHEMBL31361807 0.81 ATR (0.36) CYP4F2CYP4A11RET
SCHEMBL31327357 0.78 CYP4F2 (0.34) CYP4F2CYP4A11RET
SCHEMBL31190602 0.78 CYP4F2 (0.44) CYP4F2CYP4A11MEN1ALDH1A1KMT2A
SCHEMBL24607090 0.78 CYP4F2 (0.34) CYP4F2CYP4A11RETMAPT
SCHEMBL29712202 0.78 CYP4F2 (0.34) CYP4F2CYP4A11RETMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119183452-A LRRK2 inhibitors 布雷宁疗法公司 2024-12-24 CN disclosed
WO-2024220747-A2 FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF Lysoway Therapeutics, Inc. (US) 2024-10-24 WO disclosed