Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428600 | 0.82 | NR1H2 (0.41) | NR1H2EPHX2EPHX1HPGDUSP2 | |
| SCHEMBL34473315 | 0.82 | EPHX2 (0.40) | NR1H2EPHX2EPHX1HPGDUSP2 | |
| SCHEMBL15689694 | 0.78 | NR1H2 (0.49) | NR1H2EPHX2EPHX1KDM4EPKM | |
| SCHEMBL425587 | 0.77 | EPHX2 (0.36) | NR1H2EPHX2EPHX1USP2SMN1; SMN2 | |
| SCHEMBL30713542 | 0.75 | NR1H2 (0.47) | NR1H2EPHX2EPHX1KDM4EPKM | |
| SCHEMBL2945174 | 0.74 | NR1H2 (0.46) | NR1H2EPHX2EPHX1KDM4EPKM | |
| SCHEMBL2943268 | 0.73 | NR1H2 (0.44) | NR1H2EPHX1KDM4EPKMCHRM2 | |
| SCHEMBL22469470 | 0.72 | PIK3R1 (0.41) | NR1H2EPHX2EPHX1HPGDUSP2 | |
| SCHEMBL30713621 | 0.72 | EPHX2 (0.40) | NR1H2EPHX2EPHX1KDM4EPKM | |
| SCHEMBL1003155 | 0.71 | USP2 (0.44) | NR1H2EPHX2EPHX1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547656-A1 | INDAZOLE COMPOUNDS | Tyra Biosciences, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006897-A1 | INDAZOLE COMPOUNDS | TYRA BIOSCIENCES, INC. (US) | 2024-01-04 | — | — | WO | disclosed |