Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954933 | 0.88 | GAA (0.48) | GAAMMP1MMP13GRM2CMA1 | |
| SCHEMBL30954943 | 0.77 | GAA (0.48) | GAAMMP1MMP13GRM2CMA1 | |
| SCHEMBL27244653 | 0.73 | MMP1 (0.41) | GAAMMP1MMP13GRM2SIRT2 | |
| SCHEMBL19839346 | 0.72 | GAA (0.48) | GAAMMP1MMP13GRM2CMA1 | |
| SCHEMBL30954984 | 0.72 | GAA (0.43) | GAAMMP1MMP13GRM2CMA1 | |
| SCHEMBL30954968 | 0.72 | GAA (0.43) | GAAMMP1MMP13GRM2CMA1 | |
| SCHEMBL30954901 | 0.72 | GAA (0.43) | GAAMMP1MMP13GRM2CMA1 | |
| SCHEMBL16759341 | 0.71 | GAA (0.50) | GAAMMP1MMP13GRM2CMA1 | |
| SCHEMBL17062184 | 0.71 | GAA (0.50) | GAAMMP1MMP13GRM2CMA1 | |
| SCHEMBL17035198 | 0.71 | AR (0.50) | GAAMMP1MMP13GRM2CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113395993-B | Heterocyclic compounds and their use | 武田药品工业株式会社 | 2024-02-20 | — | — | CN | disclosed |