Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439800 | 1.00 | AXL (0.56) | AXLMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL4724843 | 0.85 | MKNK1 (0.56) | AXLMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL16405695 | 0.84 | AXL (0.61) | AXLMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL14003400 | 0.82 | CYP2A6 (0.54) | MKNK1MKNK2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL145074 | 0.82 | AXL (0.59) | AXLMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL16405697 | 0.82 | AXL (0.51) | AXLMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL22206280 | 0.81 | ABL1 (0.63) | AXLMKNK1MKNK2MEN1PSIP1 | |
| SCHEMBL29394740 | 0.81 | CYP2A6 (0.61) | MKNK1MKNK2CYP2A6CYP3A4CYP2E1 | |
| SCHEMBL16405701 | 0.81 | AXL (0.50) | AXLMKNK1MKNK2MEN1PSIP1 | |
| Hydrochloric Acid SCHEMBL6739740 | 0.81 | AXL (0.58) | AXLMKNK1MKNK2MEN1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536637-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Nico Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023240084-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |