Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.59 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7090061 | 0.98 | AXL (0.58) | AXLMEN1PSIP1MKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL6739740 | 0.98 | AXL (0.58) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL16405695 | 0.87 | AXL (0.61) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL16405691 | 0.82 | MKNK1 (0.56) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL13745220 | 0.82 | TDO2 (0.54) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL3946385 | 0.82 | IDO1 (0.53) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL30714540 | 0.82 | AXL (0.56) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL1439800 | 0.82 | AXL (0.56) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL6171120 | 0.82 | CYP2A6 (0.51) | AXLMEN1PSIP1MKNK1MKNK2 | |
| SCHEMBL2649494 | 0.82 | AXL (0.56) | AXLMEN1PSIP1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| JP-4445553-B2 | — | — | 2010-04-07 | — | — | JP | claimed |
| EP-1752192-B1 | Oxidizing hair coloring agents containing m-Aminophenol derivatives | PROCTER & GAMBLE (US) | 2010-02-03 | — | — | EP | claimed |
| US-7632591-B2 | Branched multiblock polybenzimidazole-benzamide copolymer and method for preparing the same, electrolyte membrane and paste/gel prepared therefrom | LG CHEM, LTD. (KR) | 2009-12-15 | — | — | US | claimed |
| CN-100549003-C | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2009-10-14 | — | — | CN | claimed |
| US-7491244-B2 | Oxidizing hair coloring agents containing m-aminophenol derivatives | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | claimed |
| EP-1670423-B1 | DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-10-08 | — | — | EP | claimed |
| JP-2008512561-A | — | — | 2008-04-24 | — | — | JP | claimed |
| CN-100358887-C | m-aminophenol derivatives and dyes containing these compounds | P & G CLAIROL INC (US) | 2008-01-02 | — | — | CN | claimed |
| CN-100349886-C | 1, 3-dihydroxybenzene derivatives and coloring agents containing the same | WELLA AG (US) | 2007-11-21 | — | — | CN | claimed |
| US-20030172470-A1 | Colouring agents for keratin fibres containing (1.1'-biphenyl)-2.4-diamine derivatives in addition to novel (1.1'-biphenyl)-2.4-diamine-derivatives | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-09-18 | — | — | US | claimed |
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-09-18 | — | — | US | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-20030093867-A1 | Dyes for keratin fibres containing 1,3-diamino-4-heteroarylbenzene derivatives and novel 1,3-diamino-4-heteroarylbenzene derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-05-22 | — | — | US | claimed |
| US-6503282-B1 | Composition for coloring keratin fibers based on a developer-coupler combination characterized in that it contains as the coupler 3-(2,4-diaminophenoxy)-1-propanol and as the developer ring and having general formula (I) | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-07 | — | — | US | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1166749-A2 | Composition and process for dyeing keratinic fibres | Wella Aktiengesellschaft (DE) | 2002-01-02 | — | — | EP | claimed |
| EP-1158954-A1 | MEANS AND METHOD FOR DYING KERATINIC FIBRES | Wella Aktiengesellschaft (DE) | 2001-12-05 | — | — | EP | claimed |
| WO-2001051019-A1 | MEANS AND METHOD FOR DYING KERATINIC FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2001-07-19 | — | — | WO | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030093867-A1 | Dyes for keratin fibres containing 1,3-diamino-4-heteroarylbenzene derivatives and novel 1,3-diamino-4-heteroarylbenzene derivatives | KRT18, DSP, TUBB4B | AXL 1365/4885MEN1 3993/4885PSIP1 3563/4885 |
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | AOC1, DPYD, NDUFB4 | AXL 1584/4885MEN1 4505/4885PSIP1 3117/4885 |
| US-20030172470-A1 | Colouring agents for keratin fibres containing (1.1'-biphenyl)-2.4-diamine derivatives in addition to novel (1.1'-biphenyl)-2.4-diamine-derivatives | KRT18, DSP, DSG1 | AXL 2853/4885MEN1 3507/4885PSIP1 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.