Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP7 | P09237 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26696044 | 1.00 | CYP4F2 (0.34) | CYP4F2CYP4A11OPRL1ADAM17MMP3 | |
| SCHEMBL30714572 | 0.93 | ANO1 (0.33) | CYP4F2CYP4A11OPRL1ADAM17MMP3 | |
| SCHEMBL26696014 | 0.93 | ANO1 (0.33) | CYP4F2CYP4A11OPRL1ADAM17MMP3 | |
| SCHEMBL30714574 | 0.93 | CD38 (0.33) | CYP4F2CYP4A11OPRL1ADAM17MMP3 | |
| SCHEMBL26875162 | 0.93 | GRM2 (0.33) | OPRL1ADAM17MMP3MMP7CXCR2 | |
| SCHEMBL30714552 | 0.92 | ADAM17 (0.31) | OPRL1ADAM17MMP3MMP7CXCR2 | |
| SCHEMBL30714673 | 0.89 | CD38 (0.35) | OPRL1ADAM17MMP3MAPTL3MBTL1 | |
| SCHEMBL30714699 | 0.87 | ADAM17 (0.39) | ADAM17MMP3MMP7ADAMTS4ADAMTS1 | |
| SCHEMBL30714680 | 0.84 | SCN9A (0.38) | OPRL1ADAM17MMP13CACNA1GCACNA1H | |
| SCHEMBL30714603 | 0.83 | ADAM17 (0.34) | OPRL1ADAM17MMP13CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499624-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023230540-A2 | INDAZOLE DERIVATIVES FOR TREATING TRPM3-MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |