SCHEMBL30714769

SCHEMBL30714769

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nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1LG2 Q9BQ51 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MME P08473 1/20 0.40
PLA2G2A P14555 1/20 0.38
PLA2G5 P39877 1/20 0.38
POLB P06746 1/20 0.38
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
ERAP2 Q6P179 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
CTSD P07339 1/20 0.36
BACE1 P56817 1/20 0.36
DPP4 P27487 1/20 0.36
DPP8 Q6V1X1 1/20 0.36
DPP9 Q86TI2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16870893 0.96 PDCD1LG2 (0.47) PDCD1LG2CD274ALDH1A1SMN1; SMN2MME
SCHEMBL29777795 0.96 PDCD1LG2 (0.47) PDCD1LG2CD274ALDH1A1SMN1; SMN2MME
SCHEMBL29531582 0.96 PDCD1LG2 (0.47) PDCD1LG2CD274ALDH1A1SMN1; SMN2MME
SCHEMBL31039955 0.94 CD274 (0.50) PDCD1LG2CD274ALDH1A1SMN1; SMN2MME
SCHEMBL30148446 0.92 PDCD1LG2 (0.43) PDCD1LG2CD274MMEFNTAFNTB
SCHEMBL30122840 0.92 CD274 (0.54) PDCD1LG2CD274ALDH1A1SMN1; SMN2MME
SCHEMBL31265330 0.90 PDCD1LG2 (0.43) PDCD1LG2CD274ALDH1A1SMN1; SMN2MME
SCHEMBL30118062 0.90 BACE1 (0.44) PDCD1LG2CD274MMEFNTAFNTB
SCHEMBL30792494 0.90 PDCD1LG2 (0.43) PDCD1LG2CD274ALDH1A1SMN1; SMN2MME
SCHEMBL30272531 0.89 ALDH1A1 (0.45) PDCD1LG2CD274ALDH1A1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398195-B2 Lamp constructs comprising allergens IMMUNOMIC THERAPEUTICS, INC. (US) 2025-08-26 US disclosed
CN-116970080-B Anti-human MFAP5 monoclonal antibody and preparation method thereof, polynucleotide molecule, expression vector and host cell 优睿赛思(武汉)生物科技有限公司 2024-08-13 CN disclosed
US-11826423-B2 Nucleic acids for treatment of allergies IMMUNOMIC THERAPEUTICS, INC. (US) 2023-11-28 US disclosed