SCHEMBL30714874

SCHEMBL30714874

COc1cc2oc(-c3ccc(N(C)C)cc3)c(O)c(=O)c2cc1OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.62
BACE1 P56817 2/20 0.62
ABCB1 P08183 1/20 0.58
MAPT P10636 8/20 0.57
KDM4E B2RXH2 7/20 0.57
CYP3A4 P08684 7/20 0.57
ALDH1A1 P00352 6/20 0.57
MEN1 O00255 6/20 0.57
KMT2A Q03164 6/20 0.57
CASP1 P29466 5/20 0.57
CASP7 P55210 5/20 0.57
ABCG2 Q9UNQ0 2/20 0.57
TP53 P04637 6/20 0.56
HSD17B10 Q99714 6/20 0.56
HPGD P15428 4/20 0.56
LMNA P02545 2/20 0.56
MAPK1 P28482 2/20 0.54
ALOX15 P16050 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SNCA P37840 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29478212 0.87 ABCB1 (0.70) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL25227029 0.86 MAPT (0.71) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL25233130 0.86 ACHE (0.81) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL25204764 0.85 CYP1A1 (0.67) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL25205192 0.85 CYP1A1 (0.67) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL25234796 0.85 KDM4E (0.65) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL25230489 0.84 CYP1B1 (0.65) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL30397364 0.84 ABCB1 (0.79) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL25235022 0.84 ABCB1 (0.79) ACHEBACE1ABCB1MAPTKDM4E
SCHEMBL14697046 0.83 SNCA (0.56) ACHEBACE1MAPTKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023242454-A1 HYBRID MATERIAL FOR DETECTING ACID AND BASE VAPOURS UNIVERSIDAD DE CASTILLA LA MANCHA (ES) 2023-12-21 WO disclosed