Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30715195 | 0.88 | SLC6A7 (0.54) | SLC6A7CYP2C9MEN1KMT2ACYP2C19 | |
| SCHEMBL25272191 | 0.81 | TIPARP (0.60) | SLC6A7CYP2C9MEN1KMT2ATIPARP | |
| SCHEMBL30390234 | 0.81 | TIPARP (0.60) | SLC6A7CYP2C9MEN1KMT2ATIPARP | |
| SCHEMBL25075527 | 0.81 | SLC6A7 (0.52) | SLC6A7CYP2C9MEN1KMT2ACYP2C19 | |
| SCHEMBL27233726 | 0.80 | IDO1 (0.51) | SLC6A7TIPARPLMNAHTTSLC6A9 | |
| SCHEMBL30165123 | 0.80 | SLC6A7 (0.60) | SLC6A7MEN1KMT2ATIPARPALDH1A1 | |
| SCHEMBL30165131 | 0.80 | SLC6A7 (0.54) | SLC6A7CYP2C9MEN1KMT2ACYP2C19 | |
| SCHEMBL24962327 | 0.79 | IDO1 (0.52) | SLC6A7CYP2C9MEN1KMT2ACYP2C19 | |
| SCHEMBL18825848 | 0.79 | TIPARP (0.51) | SLC6A7TIPARPLMNASLC6A9KDM4E | |
| SCHEMBL28982905 | 0.79 | SLC6A7 (0.48) | SLC6A7CYP2C9MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377665-A | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-01-09 | — | — | CN | disclosed |