Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370589 | 0.80 | PNP (0.46) | PNPPRKCIMAPTKDM4ERAD52 | |
| SCHEMBL28175860 | 0.79 | LMNA (0.46) | PNPMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL28871076 | 0.79 | PNP (0.48) | PNPPRKCIMAPTKDM4ERAD52 | |
| SCHEMBL7035002 | 0.76 | PNP (0.46) | PNPPRKCIMAPTKDM4ERAD52 | |
| SCHEMBL7032604 | 0.76 | MAPT (0.49) | PNPPRKCIMAPTKDM4ERAD52 | |
| SCHEMBL25413144 | 0.76 | LMNA (0.40) | PNPMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL7028881 | 0.76 | PNP (0.46) | PNPPRKCIMAPTKDM4ERAD52 | |
| SCHEMBL4157390 | 0.76 | PARP1 (0.41) | PNPMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL7090535 | 0.76 | PNP (0.46) | PNPPRKCIMAPTKDM4ERAD52 | |
| SCHEMBL2915004 | 0.76 | PNP (0.42) | PNPPRKCIMAPTKDM4ERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992310-B | One group replaces benzo heterocyclic amine derivant and preparation method thereof and the related application as IMPDH inhibitor | 中国医学科学院医药生物技术研究所 | 2016-07-06 | — | — | CN | disclosed |
| US-7790025-B2 | External gradient chromatofocusing | CRYOBIOPHYSICA, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20070144973-A1 | External gradient chromatofocusing | CRYOBIOPHYSICA, INC. (US) | 2007-06-28 | — | — | US | disclosed |
| EP-1628729-A2 | EXTERNAL GRADIENT CHROMATOFOCUSING | Cryobiophysica, Inc. (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004103519-A2 | EXTERNAL GRADIENT CHROMATOFOCUSING | CRYOBIOPHYSICA, INC. (US) | 2004-12-02 | — | — | WO | disclosed |
| US-20030226769-A1 | Kit for assaying saccharified protein | SODE KOJI (JP) | 2003-12-11 | — | — | US | disclosed |