⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509760 | 0.76 | — | — | |
| SCHEMBL16333875 | 0.74 | — | — | |
| SCHEMBL9529183 | 0.74 | — | — | |
| SCHEMBL5773093 | 0.74 | — | — | |
| SCHEMBL5179873 | 0.70 | — | — | |
| SCHEMBL1043281 | 0.69 | — | — | |
| SCHEMBL4586792 | 0.67 | — | — | |
| SCHEMBL11004269 | 0.67 | PRSS1 (0.33) | — | |
| SCHEMBL311359 | 0.67 | TRPA1 (0.38) | — | |
| SCHEMBL25151 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018003-B2 | Substituted pyrimidines as matrix metalloproteinase-9 hemopexin domain inhibitors | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-06-25 | — | — | US | disclosed |
| US-20210309616-A1 | SUBSTITUTED QUINAZOLINES AS MATRIX METALLOPROTEINASE-9 HEMOPEXIN DOMAIN INHIBITORS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2021-10-07 | — | — | US | disclosed |
| CN-113038954-A | Combination for treating cancer | 日东电工株式会社 | 2021-06-25 | — | — | CN | disclosed |
| US-11040947-B2 | Substituted quinazolines as matrix metalloproteinase-9 hemopexin domain inhibitors | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-06-22 | — | — | US | disclosed |
| US-10844006-B2 | Trisamide compounds and compositions comprising the same | MILLIKEN & COMPANY (US) | 2020-11-24 | — | — | US | disclosed |
| EP-3426639-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | Milliken & Company (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20170260129-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2017-09-14 | — | — | US | disclosed |
| WO-2017156099-A1 | TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY (US) | 2017-09-14 | — | — | WO | disclosed |
| US-7790793-B2 | Amide nucleating agent compositions | CIBA SPECIALTY CHEM. CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090062358-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | CANO IVAN COLLADO | 2009-03-05 | — | — | US | disclosed |
| CN-1479728-A | Peroxisome proliferator activated receptor alpha agonists | — | 2004-03-03 | — | — | CN | disclosed |
| US-5639882-A | CHEMICAL INTERMEDIATES FOR FORMING VIRICIDES INHIBITING LENTIVIRUSES | G. D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5637707-A | STEREOSELECTIVELY ADDING ORGANONETALLIC REAGENT BY NUCLEOPHILIC ADDITION TO KETONE COMPOUND | G. D. SEARLE & CO. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0566556-B1 | 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds | SEARLE & CO (US) | 1996-07-03 | — | — | EP | disclosed |
| US-5530132-A | VIRICIDES, HIV VIRUS | G. D. SEARLE & CO. (US) | 1996-06-25 | — | — | US | disclosed |
| US-5523406-A | STEREOSPECIFIC ALKYLATION BY NUCLEOPHILIC ADDITION AT C-2 WITH A GRIGNARD REAGENT | G. D. SEARLE & CO. (US) | 1996-06-04 | — | — | US | disclosed |
| US-5502193-A | VIRICIDES FOR AIDS | G. D. SEARLE & CO. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5350854-A | AIDS treatment | G. D. SEARLE & CO. (US) | 1994-09-27 | — | — | US | disclosed |
| US-5258518-A | Antiviral agents, anti-HIV activity | G. D. SEARLE & CO. (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0566556-A1 | 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds | G.D. Searle & Co. (US) | 1993-10-20 | — | — | EP | disclosed |