Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.45 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19918771 | 0.87 | CDK2 (0.43) | CDK2GSK3BCSNK2A1CDK9CDK7 | |
| SCHEMBL15224594 | 0.84 | CDK2 (0.40) | CDK2GSK3BCDK5CDK5R1CDK9 | |
| SCHEMBL15224593 | 0.84 | CDK2 (0.40) | CDK2GSK3BCDK5CDK5R1CDK9 | |
| SCHEMBL18072717 | 0.83 | CDK2 (0.41) | CDK2GSK3BCDK5CDK5R1CDK9 | |
| SCHEMBL16659552 | 0.82 | CDK2 (0.40) | CDK2GSK3BCDK5CDK5R1CDK9 | |
| SCHEMBL26696916 | 0.81 | EGFR (0.48) | CDK2CSNK2A1CDK9CDK7CCNH | |
| SCHEMBL30716256 | 0.81 | EGFR (0.48) | CDK2CSNK2A1CDK9CDK7CCNH | |
| SCHEMBL15242603 | 0.80 | CDK2 (0.37) | CDK2GSK3BCDK5CDK5R1CDK9 | |
| SCHEMBL9927210 | 0.79 | CDK2 (0.52) | CDK2CDK5CDK5R1CDK9CCNT1 | |
| SCHEMBL15241425 | 0.79 | CDK2 (0.41) | CDK2GSK3BCDK5CDK5R1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |