Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 6/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.36 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | CCNH | P51946 | 2/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CCNK | O75909 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26697039 | 0.81 | CCNT1 (0.32) | DYRK1AGSK3BCDK7CCNHMNAT1 | |
| SCHEMBL30716336 | 0.81 | CCNT1 (0.32) | DYRK1AGSK3BCDK7CCNHMNAT1 | |
| SCHEMBL24588201 | 0.69 | CLK1 (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL29699138 | 0.69 | CLK1 (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL25600778 | 0.69 | CLK1 (0.73) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL24588145 | 0.69 | CLK1 (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL30439297 | 0.69 | CLK1 (0.73) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL29699079 | 0.69 | CLK1 (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL19100699 | 0.66 | CDK5 (0.71) | CLK1CDK5CDK5R1DYRK1AGSK3B | |
| SCHEMBL24588844 | 0.66 | DYRK1A (0.53) | CLK1CDK5CDK5R1DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227125-A1 | NEW FUSED-HETEROCYCLIC COMPOUND AS CDK INHIBITOR AND USE THEREOF | 杭州德睿智药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |