SCHEMBL30716535

SCHEMBL30716535

COc1cc2nccc(Oc3ccc(NC(=O)c4nccn(-c5ccc(F)cc5)c4=O)cc3F)c2cc1OC

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MET P08581 18/20 0.80
AXL P30530 6/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30716534 0.94 MET (0.71) METAXL
SCHEMBL30716505 0.94 MET (0.70) METAXL
SCHEMBL30716521 0.90 KDR (0.67) METAXL
SCHEMBL30716506 0.89 MET (0.77) MET
SCHEMBL30716541 0.89 MET (0.77) MET
SCHEMBL23147296 0.88 MET (0.63) METAXL
SCHEMBL29764787 0.88 MET (0.63) METAXL
SCHEMBL30716495 0.88 MET (0.76) METAXL
SCHEMBL2479034 0.88 MET (0.79) METAXL
SCHEMBL30716456 0.88 MET (0.77) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343046-A Novel 3-oxo-4-substituted aryl-3, 4-dihydropyrazine-2-carboxamide compound and application thereof 辽宁大学 2024-01-05 CN disclosed