Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 9/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716642 | 1.00 | EIF2AK4 (0.38) | EIF2AK4TRPV3GPR119NTRK1FLT3 | |
| SCHEMBL25338902 | 0.87 | EIF2AK4 (0.43) | EIF2AK4TRPV3NTRK1FLT3SYK | |
| SCHEMBL30698347 | 0.81 | ALK (0.38) | TRPV3GPR119NTRK1 | |
| SCHEMBL27370361 | 0.80 | FLT3 (0.41) | FLT3SYK | |
| SCHEMBL27368391 | 0.80 | FLT3 (0.41) | FLT3SYK | |
| SCHEMBL24574154 | 0.79 | FLT3 (0.51) | FLT3USP30SYKIDH1 | |
| SCHEMBL24574159 | 0.79 | FLT3 (0.51) | FLT3USP30SYKIDH1 | |
| SCHEMBL24574171 | 0.79 | FLT3 (0.47) | EIF2AK4FLT3USP30 | |
| SCHEMBL27368267 | 0.78 | FLT3 (0.43) | FLT3 | |
| SCHEMBL25335157 | 0.78 | EIF2AK4 (0.42) | EIF2AK4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250431-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-12-28 | — | — | WO | disclosed |