Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24667440 | 1.00 | PRMT5 (0.42) | PRMT5WDR77GRM5GRM3MCHR1 | |
| SCHEMBL24667376 | 0.89 | GRM5 (0.40) | PRMT5WDR77GRM5MCHR1ADAM17 | |
| SCHEMBL29987263 | 0.89 | GRM5 (0.40) | PRMT5WDR77GRM5MCHR1ADAM17 | |
| SCHEMBL29986704 | 0.86 | CSNK1A1 (0.39) | PRMT5WDR77GRM5ADAM17 | |
| SCHEMBL24667377 | 0.86 | CSNK1A1 (0.39) | PRMT5WDR77GRM5ADAM17 | |
| SCHEMBL24667425 | 0.85 | HRH3 (0.33) | PRMT5WDR77MCHR1ADAM17 | |
| SCHEMBL24667586 | 0.82 | PRMT5 (0.45) | PRMT5WDR77GRM5GRM3MCHR1 | |
| SCHEMBL29986992 | 0.82 | PRMT5 (0.45) | PRMT5WDR77GRM5GRM3MCHR1 | |
| SCHEMBL24667583 | 0.79 | GRM5 (0.36) | GRM5 | |
| SCHEMBL24667401 | 0.79 | GRM5 (0.36) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412960-A | Isoindolinone compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2024-01-16 | — | — | CN | disclosed |