Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076329 | 0.84 | ALDH1A1 (0.38) | KDM4EALDH1A1CFTROPRK1SMN1; SMN2 | |
| SCHEMBL3076346 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1CFTROPRK1SMN1; SMN2 | |
| SCHEMBL3058649 | 0.75 | KDM4E (0.34) | KDM4EALDH1A1CFTRSMN1; SMN2HPGD | |
| SCHEMBL3064685 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1CFTRSMN1; SMN2HPGD | |
| SCHEMBL29148117 | 0.71 | NR4A2 (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL3074035 | 0.70 | CYP3A4 (0.38) | KDM4EALDH1A1CFTRSMN1; SMN2HPGD | |
| SCHEMBL30280904 | 0.70 | PDK2 (0.41) | KDM4EALDH1A1CFTROPRK1SMN1; SMN2 | |
| SCHEMBL10546858 | 0.70 | SERPINH1 (0.38) | KDM4EALDH1A1CFTRSMN1; SMN2MEN1 | |
| SCHEMBL3058533 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1CFTRSMN1; SMN2HPGD | |
| SCHEMBL8545244 | 0.69 | ALDH1A1 (0.37) | KDM4EALDH1A1CFTRSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| EP-2167484-B1 | CONDENSED ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| EP-2167484-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | Syngeta Participations AG (CH) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009010260-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273830-A1 | NOVEL INSECTICIDES | NR5A2, NR2C2, NOX5 | KDM4E 2195/4885ALDH1A1 1573/4885CFTR 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.