SCHEMBL30717006

SCHEMBL30717006

CCOC(=O)CS(=O)(=O)Nc1ccc(C(=O)Nc2cc(C)cc(N3CCC(F)(F)CC3)n2)c(N2CC[Si](C)(C)CC2)c1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27376385 1.00 KIF18A (0.69) KIF18A
SCHEMBL30717094 0.92 KIF18A (0.66) KIF18A
SCHEMBL27375640 0.92 KIF18A (0.66) KIF18A
SCHEMBL27375957 0.90 KIF18A (0.65) KIF18A
SCHEMBL30717015 0.90 KIF18A (0.65) KIF18A
SCHEMBL27376387 0.90 KIF18A (0.84) KIF18A
SCHEMBL30717058 0.86 KIF18A (0.66) KIF18A
SCHEMBL27376350 0.86 KIF18A (0.66) KIF18A
SCHEMBL30717136 0.85 KIF18A (0.69) KIF18A
SCHEMBL27375312 0.85 KIF18A (0.69) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572855-A1 INHIBITORS OF KIF18A AND USES THEREOF Accent Therapeutics, Inc. (US) 2025-06-25 — — EP disclosed
WO-2024039829-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-02-22 — — WO disclosed
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