SCHEMBL3071716

SCHEMBL3071716

O=C(O)CC(C(=O)O)C(O)C(=O)OC(CC(=O)O)(CC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
CPT2 P23786 1/20 0.35
ACLY P53396 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5862554 0.85 ACLY (0.38) CPT2ACLY
SCHEMBL1553184 0.84 TSHR (0.39) CPT2ACLY
Ammonia Solution, Strong SCHEMBL9273494 0.83 CPT2 (0.36) TDP1CPT2ACLY
Ammonia Solution, Strong SCHEMBL6522827 0.83 CPT2 (0.36) TDP1CPT2ACLY
SCHEMBL9236937 0.83 CPT2 (0.36) CPT2ACLY
Ammonia Solution, Strong SCHEMBL10939985 0.83 CPT2 (0.36) TDP1CPT2ACLY
SCHEMBL27534725 0.82 CPT2 (0.35) CPT2ACLY
SCHEMBL3071719 0.81 TDP1 (0.38) TDP1CPT2ACLY
SCHEMBL290602 0.80 SMN1; SMN2 (0.41) TDP1CPT2ACLYSMN1; SMN2SLC22A6
Hydrochloric Acid SCHEMBL11284194 0.79 SMN1; SMN2 (0.40) TDP1CPT2ACLYSMN1; SMN2SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116829131-B Olanzapine transdermal drug delivery system and preparation method and application thereof 新领医药技术(深圳)有限公司 2024-05-07 CN disclosed
CN-117815210-A Risperidone transdermal application system and preparation method and application thereof 新领医药技术(深圳)有限公司 2024-04-05 CN disclosed
CN-117157062-A Transdermal patch for inhibiting drug crystallization and preparation method thereof 新领医药技术(深圳)有限公司 2023-12-01 CN disclosed
CN-116829131-A Olanzapine transdermal drug delivery system and preparation method and application thereof 新领医药技术(深圳)有限公司 2023-09-29 CN disclosed
EP-3130676-A1 MUTANT E. COLI STRAIN WITH INCREASED SUCCINIC ACID PRODUCTION Rice University (US) 2017-02-15 EP disclosed
EP-1781797-B1 MUTANT E. COLI STRAIN WITH INCREASED SUCCINIC ACID PRODUCTION RICE UNIVERSITY (US) 2016-10-19 EP disclosed
US-20160117440-A1 SYSTEM AND METHOD FOR AUTOMATED PREDICTION OF VULNERABILITIES IN BIOLOGICAL SAMPLES MEMORIAL SLOAN-KETTERING CANCER CENTER 2016-04-28 US disclosed
EP-3004390-A1 SYSTEM AND METHOD FOR AUTOMATED PREDICTION OF VULNERABILITIES IN BIOLOGICAL SAMPLES Memorial Sloan Kettering Cancer Center (US) 2016-04-13 EP disclosed
WO-2014194092-A1 SYSTEM AND METHOD FOR AUTOMATED PREDICTION OF VULNERABILITIES IN BIOLOGICAL SAMPLES MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2014-12-04 WO disclosed
US-7790416-B2 Mutant E. coli strain with increased succinic acid production RICE UNIVERSITY (US) 2010-09-07 US disclosed
US-20070184539-A1 Mutant E. coli Strain with Increased Succinic Acid Production RICE UNIVERSITY (US) 2007-08-09 US disclosed
EP-1789569-A2 HIGH SUCCINATE PRODUCING BACTERIA Rice University (US) 2007-05-30 EP disclosed
US-7223567-B2 Mutant E. coli strain with increased succinic acid production RICE UNIVERSITY (US) 2007-05-29 US disclosed
US-20060073577-A1 High succinate producing bacteria NATIONAL SCIENCE FOUNDATION 2006-04-06 US disclosed
WO-2006034156-A2 HIGH SUCCINATE PRODUCING BACTERIA RICE UNIVERSITY (US) 2006-03-30 WO disclosed
US-20060046288-A1 Mutant E. coli strain with increased succinic acid production NATIONAL SCIENCE FOUNDATION 2006-03-02 US disclosed
US-6303351-B1 GENERATING PREFERENTIAL COMPOUND; FEED BIOREATOR OXYGEN, CARBON SOURCE AND NITROGEN SOURCE, FERMENT, CONTINUOUSLY WITHDRAW FERMENTATION PRODUCT AND RECOVER PREFERENTIAL COMPOUND Anastassiadis, Savas 2001-10-16 US disclosed
US-4075093-A PERMSELECTIVE MEMBRANE JOH. A. BENCKISER GMBH (DT) 1978-02-21 US disclosed
US-3997399-A CANDIDA LIPOLYTIC YEAST INSTITUT FRANCAIS DU PETROLE, DES CARBURANTS ET LUBRIFIANTS ET ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERES ELF (FR) 1976-12-14 US disclosed
US-3773620-A PROCESS FOR PRODUCING CITRIC ACID ISOCITRIC ACID AND MICROBIAL CELLS BY FERMENTATION KYOWA HAKKO KOGYO KK 1973-11-20 US disclosed