SCHEMBL30717166

SCHEMBL30717166

Cc1cc(NC(=O)c2ccc(NS(=O)(=O)NCCO)cc2N2CC[Si](C)(C)CC2)nc(C2CCC(F)(F)CC2)n1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30716991 0.91 KIF18A (0.66) KIF18A
SCHEMBL30717002 0.90 KIF18A (0.84) KIF18A
SCHEMBL30717191 0.90 KIF18A (0.68) KIF18A
SCHEMBL30717136 0.86 KIF18A (0.69) KIF18A
SCHEMBL27375312 0.86 KIF18A (0.69) KIF18A
SCHEMBL30717021 0.82 KIF18A (0.57) KIF18A
SCHEMBL22119408 0.81 KIF18A (1.00) KIF18A
SCHEMBL29370270 0.81 KIF18A (1.00) KIF18A
SCHEMBL30717055 0.79 KIF18A (0.55) KIF18A
SCHEMBL27376523 0.78 KIF18A (0.84) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572855-A1 INHIBITORS OF KIF18A AND USES THEREOF Accent Therapeutics, Inc. (US) 2025-06-25 — — EP disclosed
WO-2024039829-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-02-22 — — WO disclosed
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