SCHEMBL30717188

SCHEMBL30717188

C[Si]1(C)CCN(c2cc(NS(=O)(=O)CCN)ccc2C(=O)Nc2cccc(N3CCC(F)(F)CC3)n2)CC1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27375643 0.93 KIF18A (0.83) KIF18A
SCHEMBL30717049 0.92 KIF18A (0.71) KIF18A
SCHEMBL30717001 0.91 KIF18A (0.69) KIF18A
SCHEMBL27375640 0.87 KIF18A (0.66) KIF18A
SCHEMBL30717094 0.87 KIF18A (0.66) KIF18A
SCHEMBL22152140 0.84 KIF18A (1.00) KIF18A
SCHEMBL29609076 0.84 KIF18A (1.00) KIF18A
SCHEMBL30717140 0.84 KIF18A (0.83) KIF18A
SCHEMBL27376387 0.84 KIF18A (0.84) KIF18A
SCHEMBL27375637 0.83 KIF18A (0.58) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4572855-A1 INHIBITORS OF KIF18A AND USES THEREOF Accent Therapeutics, Inc. (US) 2025-06-25 — — EP disclosed
WO-2024039829-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-02-22 — — WO disclosed
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