Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 12/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31748990 | 1.00 | GRM5 (0.40) | GRM5ADORA2AADORA1DPP4DPP8 | |
| SCHEMBL30717397 | 0.94 | ADORA2A (0.42) | GRM5ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30717316 | 0.94 | ADORA2A (0.42) | GRM5ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL31748855 | 0.82 | ADORA2A (0.47) | GRM5ADORA2AADORA1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL30717593 | 0.80 | GRM5 (0.40) | GRM5ADORA2AADORA1DPP4DPP8 | |
| Trifluoroacetic Acid SCHEMBL30717702 | 0.80 | GRM5 (0.40) | GRM5ADORA2AADORA1DPP4DPP8 | |
| SCHEMBL30717448 | 0.76 | ADORA2A (0.45) | GRM5ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30717361 | 0.76 | ADORA2A (0.45) | GRM5ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30717460 | 0.74 | GRM5 (0.43) | GRM5ADORA2AADORA1NPC1RAB9A | |
| SCHEMBL30717447 | 0.74 | GRM5 (0.43) | GRM5ADORA2AADORA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572762-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | Mironid Limited (GB) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038128-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | MIRONID LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |