Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30717628 | 0.80 | GRM5 (0.46) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL31748855 | 0.80 | ADORA2A (0.47) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL30717359 | 0.79 | GRM5 (0.45) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL30717448 | 0.79 | ADORA2A (0.45) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL30717555 | 0.78 | GRM5 (0.44) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL30717403 | 0.78 | GRM5 (0.44) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL30717326 | 0.78 | GRM5 (0.44) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL30717361 | 0.78 | ADORA2A (0.45) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL30717497 | 0.76 | GRM5 (0.45) | GRM5ADORA2AADORA1RAB9ANPC1 | |
| SCHEMBL30717447 | 0.76 | GRM5 (0.43) | GRM5ADORA2AADORA1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572762-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | Mironid Limited (GB) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038128-A1 | COMPOUNDS AND THEIR USE AS PDE4 ACTIVATORS | MIRONID LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |