Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MARK3 | P27448 | 1/20 | 0.44 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27029451 | 1.00 | PIM1 (0.44) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL27029449 | 0.90 | ACHE (0.54) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL29931578 | 0.85 | DYRK1A (0.50) | ACHEDYRK1AMEN1KMT2ACYP1A2 | |
| SCHEMBL29931597 | 0.84 | ACHE (0.55) | ACHEDYRK1ACHRNA7GPR119MAPT | |
| SCHEMBL28553930 | 0.80 | DYRK1A (0.48) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL30718171 | 0.78 | NR1H2 (0.48) | ACHE | |
| SCHEMBL30076963 | 0.73 | PIM1 (0.49) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL29931570 | 0.70 | ACHE (0.54) | ACHECHRNA7GPR119MAPTLMNA | |
| SCHEMBL27029483 | 0.70 | ACHE (0.54) | ACHECHRNA7GPR119MAPTLMNA | |
| SCHEMBL13051131 | 0.70 | DYRK1A (0.42) | PIM1MARK3MAP4K2CAMK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157284-A | CTLA-4 small molecule degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |