Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718171 | 0.89 | NR1H2 (0.48) | ACHENR1H2NR1H3TRPV3CA12 | |
| SCHEMBL3274585 | 0.81 | ACHE (0.66) | ACHECHRNA7GPR119PTPN11DDB1 | |
| SCHEMBL3651086 | 0.81 | ACHE (0.57) | ACHECHRNA7GPR119PTPN11DDB1 | |
| SCHEMBL27029442 | 0.78 | ACHE (0.55) | ACHECHRNA7GPR119PTPN11DDB1 | |
| SCHEMBL30718211 | 0.78 | ACHE (0.55) | ACHECHRNA7GPR119PTPN11DDB1 | |
| SCHEMBL27029449 | 0.78 | ACHE (0.54) | ACHECHRNA7GPR119PTPN11DDB1 | |
| SCHEMBL3268731 | 0.78 | ACHE (0.58) | ACHECHRNA7GPR119PTPN11DDB1 | |
| SCHEMBL30619487 | 0.78 | NR1H2 (0.64) | NR1H2NR1H3TRPV3CA12CA9 | |
| SCHEMBL30831452 | 0.77 | ACHE (0.57) | ACHECHRNA7GPR119PTPN11DDB1 | |
| SCHEMBL26993891 | 0.77 | ACHE (0.57) | ACHECHRNA7GPR119PTPN11DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157284-A | CTLA-4 small molecule degradation agent and application thereof | 苏州国匡医药科技有限公司 | 2023-12-01 | — | — | CN | disclosed |