SCHEMBL30718481

SCHEMBL30718481

NC(=O)Cn1cc(C=O)c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.64
KMT2A Q03164 5/20 0.62
MEN1 O00255 4/20 0.62
SMN1; SMN2 Q16637 5/20 0.59
L3MBTL1 Q9Y468 2/20 0.56
IDO1 P14902 1/20 0.56
POLB P06746 1/20 0.55
LMNA P02545 1/20 0.54
HTT P42858 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1520957 1.00 ALDH1A1 (0.64) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL1250173 0.86 ALDH1A1 (0.66) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL29952467 0.86 ALDH1A1 (0.66) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL15331835 0.85 ALDH1A1 (0.56) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL8264387 0.84 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL1536915 0.82 ALDH1A1 (0.60) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL14450860 0.82 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL8690458 0.82 KMT2A (0.65) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1
SCHEMBL5475563 0.81 ALDH1A1 (0.76) ALDH1A1KMT2AMEN1SMN1; SMN2POLB
SCHEMBL2189025 0.80 ALDH1A1 (0.59) ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285511-A Indole hybridized quinolone compound and preparation method and application thereof 西南大学 2023-12-26 CN disclosed